trypanosomiasisPronunciation: /ˌtrɪp(ə)nə(ʊ)sə(ʊ)ˈmʌɪəsɪs, trɪˌpanə(ʊ)-/Definition of trypanosomiasis noun [mass noun] Medicine any tropical disease caused by trypanosomes and typically transmitted by biting insects, especially sleeping sickness and Chagas' disease. trypanosomiasis in other Oxford dictionaries Definition of trypanosomiasis in the US English dictionary