sulphanilamidePronunciation: /ˌsʌlfəˈnɪləmʌɪd/ (US sulfanilamide)Definition of sulphanilamide noun Medicine a synthetic compound with antibacterial properties which is the basis of the sulphonamide drugs. Alternative name: p-aminobenzenesulphonamide; chemical formula: (H2N)C6H4(SO2NH2) Origin: 1930s: from sulphanilic (from sulphur + aniline + -ic) + amidesulphanilamide in other Oxford dictionaries Definition of sulphanilamide in the US English dictionary