hyoscinePronunciation: /ˈhʌɪəsiːn/Definition of hyoscine noun [mass noun] Chemistry a poisonous plant alkaloid used as an anti-emetic in motion sickness and as a preoperative medication for examination of the eye. Chemical formula: C17H21NO4. It is obtained chiefly from plants of the genus Scopolia, family Solanaceae Origin: late 19th century: from modern Latin hyoscyamus (see hyoscyamine) + -ine4hyoscine in other Oxford dictionaries Definition of hyoscine in the US English dictionary