cortexPronunciation: /ˈkɔːtɛks/Definition of cortex noun (plural cortices /-tɪˌsiːz/) 1 Anatomy the outer layer of the cerebrum (the cerebral cortex), composed of folded grey matter and playing an important role in consciousness. an outer layer of another organ or body part such as a kidney (the renal cortex), the cerebellum, or a hair. 2 Botany an outer layer of tissue immediately below the epidermis of a stem or root. Derivatives corticalPronunciation: /ˈkɔːtɪk(ə)l/ adjective Origin: late Middle English: from Latin, literally 'bark'cortex in other Oxford dictionaries Definition of cortex in the US English dictionary