toxin Syllabification: (tox·in)Pronunciation: /ˈtäksin/Translate toxin | into French | into German | into Italian | into Spanish Definition of toxin noun an antigenic poison or venom of plant or animal origin, especially one produced by or derived from microorganisms and causing disease when present at low concentration in the body. Origin: late 19th century: from toxic + -in1toxin in other Oxford dictionaries Definition of toxin in the British & World English dictionary