thermonuclear Syllabification: (ther·mo·nu·cle·ar)Pronunciation: /ˌTHərmōˈn(y)o͞oklēər, -kli(ə)r/Definition of thermonuclear adjective relating to or using nuclear reactions that occur only at very high temperatures. of, relating to, or involving weapons in which explosive force is produced by thermonuclear reactions. thermonuclear in other Oxford dictionaries Definition of thermonuclear in the British & World English dictionary