takeoff Syllabification: (take·off)Pronunciation: /ˈtākˌôf, -ˌäf/Translate takeoff | into Spanish Definition of takeoff noun 1the action of becoming airborne:the plane accelerated down the runway for takeoff 2an act of mimicking someone or something:a pleasant takeoff on some Everly Brothers routinetakeoff in other Oxford dictionaries Definition of takeoff in the British & World English dictionary