sixteen Syllabification: (six·teen)Pronunciation: /sikˈstēn, ˈsikˌstēn/Translate sixteen | into French | into German | into Italian | into Spanish Definition of sixteen number equivalent to the product of four and four; one more than fifteen, or six more than ten; 16:sixteen miles east of Detroit sixteen of our eighteen patients (Roman numeral: xvi, XVI) a size of garment or other merchandise denoted by sixteen. sixteen years old:a daughter of sixteenDerivatives sixteenthPronunciation: /sikˈstēnTH, ˈsikˌstēnTH/ number Origin: Old English siextīene (see six, -teen)sixteen in other Oxford dictionaries Definition of sixteen in the British & World English dictionary