semilethal Syllabification: (sem·i·le·thal)Pronunciation: /ˌsemēˈlēTHəl, ˌsemˌī-/Definition of semilethal adjective Genetics relating to or denoting an allele or chromosomal abnormality that impairs the viability of most of the individuals homozygous for it. semilethal in other Oxford dictionaries Definition of semilethal in the British & World English dictionary