oxazole Syllabification: (ox·a·zole)Pronunciation: /ˈäksəˌzōl/Definition of oxazole noun Chemistry a volatile liquid with weakly basic properties, whose molecule contains a five-membered ring that serves as the basis of a number of medicinal drugs. A heterocyclic compound; chemical formula: C3H3NO Origin: late 19th century: from ox- 'oxygen' + azo- + -oleoxazole in other Oxford dictionaries Definition of oxazole in the British & World English dictionary