myxomatosis Syllabification: (myx·o·ma·to·sis)Pronunciation: /mikˌsōməˈtōsəs/Definition of myxomatosis noun a highly infectious and usually fatal viral disease of rabbits, causing swelling of the mucous membranes and inflammation and discharge around the eyes. myxomatosis in other Oxford dictionaries Definition of myxomatosis in the British & World English dictionary