mainsail Syllabification: (main·sail)Pronunciation: /ˈmānsəl, -ˌsāl/Translate mainsail | into Italian Definition of mainsail noun the principal sail of a ship, especially the lowest sail on the mainmast in a square-rigged vessel. the sail set on the after side of the mainmast in a fore-and-aft-rigged vessel. mainsail in other Oxford dictionaries Definition of mainsail in the British & World English dictionary