insane

adjective

• in a state of mind that prevents normal perception, behavior, or social interaction; seriously mentally ill:certifying patients as clinically insane he had gone insane
• (of an action or quality) characterized or caused by madness:charging headlong in an insane frenzy his eyes glowing with insane fury
• in a state of extreme annoyance or distraction:a fly whose buzzing had been driving me insane
• (of an action or policy) extremely foolish; irrational or illogical:she had an insane desire to giggle