hypogonadism Syllabification: (hy·po·gon·ad·ism)Pronunciation: /ˌhīpōˈgōnaˌdizəm/Definition of hypogonadism noun Medicine reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries). Derivatives hypogonadalPronunciation: /ˌhīpəˌgōˈnadl/ adjective hypogonadicPronunciation: /ˌhīpəgōˈnadik/ noun & adjective hypogonadism in other Oxford dictionaries Definition of hypogonadism in the British & World English dictionary