hydrophilic Syllabification: (hy·dro·phil·ic)Pronunciation: /ˌhīdrəˈfilik/Definition of hydrophilic adjective having a tendency to mix with, dissolve in, or be wetted by water. The opposite of hydrophobic.Derivatives hydrophilicityPronunciation: /-fəˈlisitē/ noun hydrophilic in other Oxford dictionaries Definition of hydrophilic in the British & World English dictionary