hydrofluorocarbon Syllabification: (hy·dro·fluor·o·car·bon)Pronunciation: /ˌhīdrōˈflo͝orəˌkärbən/ (abbreviation: HFC)Definition of hydrofluorocarbon noun Chemistry any of a class of partly chlorinated and fluorinated hydrocarbons, used as an alternative to chlorofluorocarbons in foam production, refrigeration, and other processes. hydrofluorocarbon in other Oxford dictionaries Definition of hydrofluorocarbon in the British & World English dictionary