halophile Syllabification: (hal·o·phile)Pronunciation: /ˈhaləˌfīl/Definition of halophile noun Ecology an organism, especially a microorganism, that grows in or can tolerate saline conditions. Derivatives halophilicPronunciation: /ˌhaləˈfilik/ adjective halophile in other Oxford dictionaries Definition of halophile in the British & World English dictionary