griffon Syllabification: (grif·fon)Pronunciation: /ˈgrifən/Definition of griffon noun 1a dog of any of several terrierlike breeds originating in northwestern Europe. (also Brussels griffon) a dog of a toy breed with a flat face and upturned chin. 2 (also griffon vulture) a large Old World vulture with predominantly pale brown plumage. Genus Gyps, family Accipitridae: four species, in particular the Eurasian G. fulvus and the African Ruppell’s griffon (G. ruepelli) 3variant spelling of griffin.Origin: Middle English (in sense 2 and sense 3): variant of griffin; sense 1 was adopted from French in the 18th centurygriffon in other Oxford dictionaries Definition of griffon in the British & World English dictionary