ependyma Syllabification: (ep·en·dy·ma)Pronunciation: /əˈpendəmə/Definition of ependyma noun Anatomy the thin membrane of glial cells lining the ventricles of the brain and the central canal of the spinal cord. Derivatives ependymal adjective Origin: late 19th century: from Greek ependuma, from ependuein 'put on over'ependyma in other Oxford dictionaries Definition of ependyma in the British & World English dictionary