dioxane Syllabification: (di·ox·ane)Pronunciation: /dīˈäkˌsān/ (also dioxan /-ˈäksän, -sən/)Definition of dioxane noun Chemistry a colorless, toxic liquid used as an organic solvent. A heterocyclic compound with a ring of four carbon and two oxygen atoms; chemical formula: C4H8O2 Origin: early 20th century: from di-1 'two' + ox- 'oxygen' + -an(or -ane2)dioxane in other Oxford dictionaries Definition of dioxane in the British & World English dictionary