cystectomy Syllabification: (cys·tec·to·my)Pronunciation: /sisˈtektəmē/Definition of cystectomy noun 1 (plural cystectomies) a surgical operation to remove the urinary bladder. 2a surgical operation to remove an abnormal cyst:an ovarian cystectomycystectomy in other Oxford dictionaries Definition of cystectomy in the British & World English dictionary