cyclize Syllabification: (cy·clize)Pronunciation: /ˈsīk(ə)ˌlīz/Definition of cyclize verb Chemistry undergo or cause to undergo a reaction in which one part of a molecule becomes linked to another to form a closed ring. Derivatives cyclizationPronunciation: /ˌsīk(ə)ləˈzāSHən/ noun cyclize in other Oxford dictionaries Definition of cyclize in the British & World English dictionary