chorion Syllabification: (cho·ri·on)Pronunciation: /ˈkôrēˌän/Definition of chorion noun Embryology the outermost membrane surrounding an embryo of a reptile, bird, or mammal. In mammals (including humans), it contributes to the formation of the placenta. Derivatives chorionicPronunciation: /ˌkôrēˈänik/ adjective Origin: mid 16th century: from Greek khorionchorion in other Oxford dictionaries Definition of chorion in the British & World English dictionary