cephalization Syllabification: (ceph·a·li·za·tion)Pronunciation: /ˌsefələˈzāSHən/Definition of cephalization noun Zoology the concentration of sense organs, nervous control, etc., at the anterior end of the body, forming a head and brain, both during evolution and in the course of an embryo’s development. cephalization in other Oxford dictionaries Definition of cephalization in the British & World English dictionary