axoneme Syllabification: (ax·o·neme)Pronunciation: /ˈaksəˌnēm/Definition of axoneme noun Biology the central strand of a cilium or flagellum. It is composed of an array of microtubules, typically in nine pairs around two single central ones. Derivatives axonemalPronunciation: /aksəˈnēməl/ adjective Origin: early 20th century: from Greek axōn 'axis' + nēma 'thread'axoneme in other Oxford dictionaries Definition of axoneme in the British & World English dictionary