Stratford-upon-Avon Syllabification: (Strat·ford-up·on-A·von)Pronunciation: /ˈstratfərd əˌpän ˈāvən, əˌpôn, ˈāˌvän/Definition of Stratford-upon-Avon a town in central England, on the Avon River; population 23,100 (est. 2009). Noted as the birth and burial place of William Shakespeare, it is the site of the Royal Shakespeare Theatre. Derivatives StratfordianPronunciation: /stratˈfôrdēən/ noun Stratford-upon-Avon in other Oxford dictionaries Definition of Stratford-upon-Avon in the British & World English dictionary