Sacramento Syllabification: (Sac·ra·men·to)Pronunciation: /ˌsakrəˈmentō/Definition of Sacramento 1a river in northern California that rises near the border with Oregon and flows about 380 miles (611 km) south to San Francisco Bay. 2the capital of California, situated on the Sacramento River, northeast of San Francisco; population 463,794 (est. 2008). Sacramento in other Oxford dictionaries Definition of Sacramento in the British & World English dictionary