Definition of Plymouth
1a port and naval base in Devon, southwestern England; population 251,900 (est. 2009). In 1620 it was the scene of the Pilgrim Fathers' departure to North America in the Mayflower. 2a town in southeastern Massachusetts, on the Atlantic coast; population 55,705 (est. 2008). The site in 1620 of the landing of the Pilgrim Fathers, it was the earliest permanent European settlement in New England. 3a city in southeastern Minnesota, northwest of Minneapolis; population 71,486 (est. 2008). 4the capital of the island of Montserrat in the Caribbean Sea. It was abandoned following the eruption of the Soufrière Hills volcano that began in 1995.