McGuffey, William Holmes Syllabification: (Mc·Guf·fey, William Holmes)Pronunciation: /mə(k)ˈgəfē/Definition of McGuffey, William Holmes (1800–1873), US public education reformer. He is best known for his series of Eclectic Readers, compiled between 1836 and 1857 and more commonly called McGuffey Readers.
