Honolulu Syllabification: (Hon·o·lu·lu)Pronunciation: /ˌhänlˈo͞olo͞o, ˌhōn-/Definition of Honolulu the capital of Hawaii, a principal port on the southeastern coast of the island of Oahu; population 374,676 (est. 2008). Honolulu in other Oxford dictionaries Definition of Honolulu in the British & World English dictionary