Euphrates Syllabification: (Eu·phra·tes)Pronunciation: /yo͞oˈfrātēz/Definition of Euphrates a river of southwestern Asia that rises in the mountains of eastern Turkey and flows for 1,700 miles (2,736 km) through Syria and Iraq to join the Tigris River to form the Shatt al-Arab waterway. Euphrates in other Oxford dictionaries Definition of Euphrates in the British & World English dictionary