Erastus Syllabification: (E·ras·tus)Pronunciation: /iˈrastəs/Definition of Erastus (1524–83), Swiss theologian and physician; Swiss name Thomas Lieber, also Liebler or Lüber. Professor of medicine at Heidelberg from 1558, he opposed the imposition of a Calvinistic system of church government in the city. Erastus in other Oxford dictionaries Definition of Erastus in the British & World English dictionary