Chamaeleon Syllabification: (Cha·mae·le·on)Pronunciation: /kəˈmēlyən, -lēən/ AstronomyDefinition of Chamaeleon a small and faint southern constellation (the Chameleon), close to the south celestial pole. (as genitive Chamaeleontis /kəˌmēlēˈäntis/) used with a preceding letter or numeral to designate a star in this constellation:the star Delta ChamaeleontisOrigin:from GreekChamaeleon in other Oxford dictionaries Definition of Chamaeleon in the British & World English dictionary