Barrymore Syllabification: (Bar·ry·more)Pronunciation: /ˈbarəˌmôr/Definition of Barrymore a US family of film and stage actors, notably Lionel (1878–1954), his sister Ethel (1879–1959), their brother John (1882–1942), and John’s granddaughter Drew (1975-). Barrymore in other Oxford dictionaries Definition of Barrymore in the British & World English dictionary