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syndrome British & World English

a group of symptoms which consistently occur together, or a condition characterized by a set of associated symptoms

syndrome X British & World English

a group of risk factors (including glucose intolerance, high triglycerides, obesity, and hypertension) that indicate predisposition to diabetes

China syndrome British & World English

a hypothetical sequence of events following the meltdown of a nuclear reactor, in which the core melts through its containment structure and deep into the earth

Down's syndrome (also Down syndrome) British & World English

a congenital disorder arising from a chromosome defect, causing intellectual impairment and physical abnormalities including short stature and a broad facial profile. It arises from a defect involving chromosome 21, usually an extra copy (trisomy-21)

Reye's syndrome British & World English

a life-threatening metabolic disorder in young children, of uncertain cause but sometimes precipitated by aspirin and involving encephalitis and liver failure

Angelman syndrome British & World English

a rare congenital disorder characterized by mental disability and a tendency to jerky movement, caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother

Cushing's syndrome British & World English

a metabolic disorder caused by overproduction of corticosteroid hormones by the adrenal cortex and often involving obesity and high blood pressure

dumping syndrome British & World English

a group of symptoms, including weakness, abdominal discomfort, and sometimes abnormally rapid bowel evacuation, occurring after meals in some patients who have undergone gastric surgery

Horner's syndrome British & World English

a condition marked by a contracted pupil, drooping upper eyelid, and local inability to sweat on one side of the face, caused by damage to sympathetic nerves on that side of the neck

Hurler's syndrome British & World English

a defect in metabolism arising from congenital absence of an enzyme, causing accumulation of lipids and mucopolysaccharides, and resulting in mental retardation, a protruding abdomen, and bone deformities including an abnormally large head

Marfan's syndrome British & World English

a hereditary disorder of connective tissue, resulting in abnormally long and thin digits and also frequently in optical and cardiovascular defects

metabolic syndrome British & World English

a cluster of biochemical and physiological abnormalities associated with the development of cardiovascular disease and type 2 diabetes

Patau's syndrome British & World English

a congenital disorder in which there are three copies of chromosome 13, 14, or 15 instead of the usual two. This results in brain, heart, and kidney defects which are usually fatal soon after birth

postviral syndrome (also postviral fatigue syndrome) British & World English

myalgic encephalomyelitis following a viral infection

Reiter's syndrome (also Reiter's disease) British & World English

a medical condition typically affecting young men, characterized by arthritis, conjunctivitis, and urethritis, and caused by an unknown pathogen, possibly a chlamydia

Sjögren's syndrome (also Sjögren's disease) British & World English

a chronic autoimmune condition characterized by degeneration of the salivary and lachrymal glands, causing dryness of the mouth and eyes

Stockholm syndrome British & World English

feelings of trust or affection felt in many cases of kidnapping or hostage-taking by a victim towards a captor

Turner's syndrome British & World English

a genetic defect in which affected women have only one X chromosome, causing developmental abnormalities and infertility

Werner's syndrome British & World English

a rare hereditary syndrome causing rapid premature ageing, susceptibility to cancer, and other disorders

Asperger's syndrome (also Asperger syndrome) British & World English

a developmental disorder related to autism and characterized by awkwardness in social interaction, pedantry in speech, and preoccupation with very narrow interests

compartment syndrome British & World English

a condition resulting from increased pressure within a confined body space, especially of the leg or forearm

fragile X syndrome British & World English

an inherited condition characterized by an X chromosome that is abnormally susceptible to damage, especially by folic acid deficiency. Affected individuals tend to have limited intellectual functions

Gulf War syndrome British & World English

a medical condition affecting many veterans of the 1991 Gulf War, characterized by fatigue, chronic headaches, and skin and respiratory disorders. Its origin is uncertain, though it has been attributed to exposure to a combination of pesticides, vaccines, and other chemicals

Klinefelter's syndrome British & World English

a syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts

Korsakoff's syndrome (also Korsakoff's psychosis) British & World English

a serious mental illness, typically the result of chronic alcoholism, characterized by disorientation and a tendency to invent explanations to cover a loss of memory of recent events

lipodystrophy syndrome British & World English

a metabolic disease in which fat distribution in the body becomes abnormal, often as a result of taking protease inhibitor drugs. Fat is lost from the face, arms, and legs, and is built up in other places, especially the breasts, abdomen, and back of the neck

locked-in syndrome British & World English

a medical condition, usually resulting from a stroke that damages part of the brainstem, in which the body and most of the facial muscles are paralysed but consciousness remains and the ability to perform certain eye movements is preserved

Munchausen's syndrome (also Munchausen syndrome) British & World English

a mental disorder in which a person repeatedly feigns severe illness so as to obtain hospital treatment

premenstrual syndrome (abbreviation: PMS) British & World English

any of a complex of symptoms (including emotional tension and fluid retention) experienced by some women in the days immediately before menstruation

Sanfilippo's syndrome British & World English

a defect in metabolism similar to Hurler’s syndrome

Tourette's syndrome (also Tourette syndrome) British & World English

a neurological disorder characterized by involuntary tics and vocalizations and often the compulsive utterance of obscenities

Lesch–Nyhan syndrome British & World English

a rare hereditary disease which affects young boys, usually causing early death. It is marked by compulsive self-mutilation of the head and hands, together with learning difficulties and involuntary muscular movements

Prader–Willi syndrome British & World English

a rare congenital disorder characterized by learning difficulties, growth abnormalities, and obsessive eating, caused especially by the absence of certain genes normally present on the copy of chromosome 15 inherited from the father

shaken baby syndrome British & World English

a condition characterized by cranial injury, retinal haemorrhage, etc. observed in infants who have been violently jolted

tall poppy syndrome British & World English

a perceived tendency to discredit or disparage those who have achieved notable wealth or prominence in public life

toxic shock syndrome (abbreviation: TSS) British & World English

acute septicaemia in women, typically caused by bacterial infection from a retained tampon or IUD

battered child syndrome British & World English

the set of symptoms, injuries, and signs of mistreatment seen on a severely or repeatedly abused child

battered woman syndrome British & World English

the set of symptoms, injuries, and signs of mistreatment seen in a woman who has been repeatedly abused by a husband or other male figure

carpal tunnel syndrome British & World English

a painful condition of the hand and fingers caused by compression of a major nerve where it passes over the carpal bones through a passage at the front of the wrist. It may be caused by continual repetitive movements or by fluid retention

chronic fatigue syndrome British & World English

a medical condition of unknown cause, with fever, aching, and prolonged tiredness and depression, typically occurring after a viral infection

economy-class syndrome British & World English

deep-vein thrombosis said to be caused by periods of prolonged immobility on long-haul flights

fetal alcohol syndrome British & World English

a congenital syndrome associated with excessive consumption of alcohol by the mother during pregnancy, and characterized by retardation of mental development and of physical growth, particularly of the skull and face

Guillain–Barré syndrome British & World English

an acute disorder of the peripheral nerves, often preceded by a respiratory infection, causing weakness and often paralysis of the limbs

irritable bowel syndrome British & World English

a widespread condition involving recurrent abdominal pain and diarrhoea or constipation, often associated with stress, depression, anxiety, or previous intestinal infection

restless legs syndrome British & World English

a disorder characterized by an unpleasant tickling or twitching sensation in the leg muscles when sitting or lying down, relieved only by moving the legs

sick building syndrome British & World English

a condition affecting office workers, typically marked by headaches and respiratory problems, attributed to unhealthy or stressful factors in the working environment such as poor ventilation

total allergy syndrome British & World English

a condition involving a wide range of symptoms thought to be caused by sensitivity to the chemical substances encountered in the modern environment. Its medical characterization is controversial

battering parent syndrome British & World English

the set of symptoms and signs indicating a psychological disorder in a parent or child-care provider resulting in a tendency toward repeated abuse of a child

Chinese restaurant syndrome British & World English

an illness marked by short attacks of weakness, numbness, palpitations, and headaches, often attributed to overconsumption of monosodium glutamate (used as a seasoning in Chinese cooking)

de Clerambault's syndrome British & World English

another term for erotomania.


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