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1cosmetics such as lipstick or powder applied to the face, used to enhance or alter the appearance: she came downstairs, her face still white under her heavy make-up [with modifier]: stage make-up [as modifier]: chief make-up artist
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2the composition or constitution of something: ozone damages the cellular make-up of plants and trees
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the combination of qualities that form a person’s temperament: a curiously unexpected timidity in his make-up
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3 Printing the arrangement of text, illustrations, etc. on a printed page: page make-up
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4 [count noun] North American a supplementary test or assignment given to a student who missed or failed the original one: I would have flunked the course but she let me write a make-up