zwitterionPronunciation: /ˈzwɪtərʌɪən, ˈtsvɪ-/Definition of zwitterion noun Chemistry a molecule or ion having separate positively and negatively charged groups. Derivatives zwitterionic adjective Origin: early 20th century: from German, from Zwitter 'a hybrid' + Ion 'ion'zwitterion in other Oxford dictionaries Definition of zwitterion in the US English dictionary