xylenePronunciation: /ˈzʌɪliːn/Definition of xylene noun [mass noun] Chemistry a volatile liquid hydrocarbon obtained by distilling wood, coal tar, or petroleum, used in fuels and solvents and in chemical synthesis. Alternative name: dimethylbenzene; chemical formula: C6H4(CH3)2; three isomers Origin: mid 19th century: from xylo- 'of wood' + -enexylene in other Oxford dictionaries Definition of xylene in the US English dictionary