xerophthalmiaPronunciation: /ˌzɪərɒfˈθalmɪə, ˌzɛ-/Definition of xerophthalmia noun [mass noun] Medicine abnormal dryness of the conjunctiva and cornea of the eye, with inflammation and ridge formation, typically associated with vitamin A deficiency. xerophthalmia in other Oxford dictionaries Definition of xerophthalmia in the US English dictionary