wormholePronunciation: /ˈwəːmhəʊl/Translate wormhole | into Italian Definition of wormhole noun 1a hole made by a burrowing insect larva or worm in wood, fruit, books, or other materials. 2 Physics a hypothetical connection between widely separated regions of space-time. wormhole in other Oxford dictionaries Definition of wormhole in the US English dictionary