valinePronunciation: /ˈveɪliːn/Definition of valine noun [mass noun] Biochemistry an amino acid which is a constituent of most proteins. It is an essential nutrient in the diet of vertebrates. Chemical formula: (CH3)2CHCH(NH2)COOH Origin: early 20th century: from val(eric acid) + -ine4valine in other Oxford dictionaries Definition of valine in the US English dictionary