tuberPronunciation: /ˈtjuːbə/Translate tuber | into German | into Italian | into Spanish Definition of tuber noun 1a much thickened underground part of a stem or rhizome, e.g. in the potato, serving as a food reserve and bearing buds from which new plants arise. a tuberous root, e.g. of the dahlia. 2 Anatomy a rounded swelling or protuberant part: [with Latin modifier]:tuber cinereumOrigin: mid 17th century: from Latin, literally 'hump, swelling'tuber in other Oxford dictionaries Definition of tuber in the US English dictionary