telophasePronunciation: /ˈtiːlə(ʊ)feɪz, ˈtɛl-/Definition of telophase noun [mass noun] Biology the final phase of cell division, between anaphase and interphase, in which the chromatids or chromosomes move to opposite ends of the cell and two nuclei are formed. Origin: late 19th century: from Greek telos 'end' + phasetelophase in other Oxford dictionaries Definition of telophase in the US English dictionary