telomerePronunciation: /ˈtiːlə(ʊ)mɪə, ˈtɛl-/Definition of telomere noun Genetics a compound structure at the end of a chromosome. Derivatives telomeric adjective Origin: 1940s: from Greek telos 'end' + meros 'part'telomere in other Oxford dictionaries Definition of telomere in the US English dictionary