tambotiePronunciation: /tamˈbʊti, -ˈbuːti, -ˈbʊəti/Definition of tambotie noun South African an African tree of the spurge family, with scented timber and caustic sap. Spirostachys africana, family Euphorbiaceae Origin: mid 19th century: from Xhosa um-Thombothi, literally 'poison tree'