synostosisPronunciation: /ˌsɪnɒˈstəʊsɪs/Definition of synostosis noun (plural synostoses /-siːz/) [mass noun] Physiology & Medicine the union or fusion of adjacent bones by the growth of bony substance, either as a normal process during growth or as the result of ankylosis. Origin: mid 19th century: from syn- 'together' + Greek osteon 'bone' + -osissynostosis in other Oxford dictionaries Definition of synostosis in the US English dictionary