superinfectionPronunciation: /suːp(ə)rɪnˈfɛkʃ(ə)n, sjuːp(ə)rɪnˈfɛkʃ(ə)n/Definition of superinfection noun [mass noun] Medicine infection occurring after or on top of an earlier infection, especially following treatment with broad-spectrum antibiotics. superinfection in other Oxford dictionaries Definition of superinfection in the US English dictionary