superhelixPronunciation: /ˈsuːpəhiːlɪks, ˈsjuːpəhiːlɪks/Definition of superhelix noun (plural superhelices) Biochemistry a helical structure formed from a number of protein or nucleic acid chains which are individually helical. Derivatives superhelical adjective superhelix in other Oxford dictionaries Definition of superhelix in the US English dictionary