stericPronunciation: /ˈstɛrɪk, ˈstɪərɪk/Definition of steric adjective Chemistry relating to the spatial arrangement of atoms in a molecule, especially as it affects chemical reactions. Derivatives sterically adverb Origin: late 19th century: formed irregularly from Greek stereos 'solid' + -icsteric in other Oxford dictionaries Definition of steric in the US English dictionary