solubilizePronunciation: /ˈsɒljʊbɪlʌɪz/ (also solubilise)Definition of solubilize verb [with object] technical make (a substance) soluble or more soluble: proteins were solubilized by heating for 5 min in protein dissociation bufferDerivatives solubilizationPronunciation: /-ˈzeɪʃ(ə)n/ noun solubilize in other Oxford dictionaries Definition of solubilize in the US English dictionary